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In KS, a mutation in the FERMT1 gene results in loss of function, leading to keratinocyte detachment, duplication of the lamina densa, and multiple cleavage planes at different levels of the dermoepidermal junction, beginning at birth.5,7 From the first years of life all 4 patients presented skin fragility that subsequently diminished, leaving patients with cutaneous atrophy and poikiloderma predominantly in photo-exposed areas

Sorry doc but I DO care and just because you are used to patients that bleat like well trained sheep that is your problem

If the legal limit for the volume of e-liquid was ignored on such a grand scale, what other rules have they chosen to ignore

A recent systematic review and meta-analysis found that patients on cytisine had 1.74 (95% CI: 1.382.19) times higher successful continuous abstinence at the longest follow-up than those using a placebo 111